Luca Di Noto

VP, Technical Operations at Jasper Therapeutics

Dr. Di Noto joined Jasper Therapeutics in 2020 as Vice President, Technical Operations. He has extensive industry experience in process development, process scale-up, technology transfer, cGMP manufacturing, and regulatory submissions for biologic drugs. Before joining Jasper, he was at Portola Pharmaceuticals where he worked for five years as the Head of Drug Substance manufacturing, overseeing the Andexxa® program. As a member of the Technical Operation Senior Leadership Team, Dr. Di Noto played a vital role in building a robust manufacturing program, developing a global contract manufacturing network strategy, and achieving successful approval of a second-generation version of Andexxa, both in the United States and Europe. Before joining Portola, Dr. Di Noto worked at Alexion Pharmaceuticals where he developed processes for many of its lead candidate drugs both in early and late stages of development. Prior to that, he worked at Amgen. Dr. Di Noto started his career at the National Institutes of Health where he was a Research Fellow at the National Heart, Lung and Blood Institute).


  • VP, Technical Operations

    Current role


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