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Jason Ruth

Jason Ruth, Ph.D. joined MRL Ventures as a Partner in 2022. Previously, he helped establish 5AM Venture’s public fund where he led investments in Janux Therapeutics, Disc Medicine, and Avidity Biosciences. He played early operating roles in Vor Biopharma (NASDAQ: VOR), Entrada Therapeutics (NASDAQ: TRDA), and Seeker Therapeutics, which he also co-founded, and previously held board observer roles at Expansion Therapeutics, Vor Biopharma (NASDAQ:VOR), Homology Medicines (NASDAQ: FIXX), Cabaletta Bio (NASDAQ: CABA), and Entrada Therapeutics (NASDAQ: TRDA). Earlier in his career he was a Postdoctoral Fellow with Levi Garraway at the Broad Institute of MIT and Harvard, where he studied PRMT5 dependency in MTAP-null cancers. Dr. Ruth volunteers as Chief Scientific Officer and as a Scientific Advisory Board member for the Castleman Disease Collaborative Network. He received his Ph.D. in Bioengineering from the University of Pennsylvania as an HHMI-Interfaces Fellow and received a Ruth L. Kirschstein NRSA Predoctoral Fellowship to investigate cancer immunology with Lewis Chodosh. Dr. Ruth received a B.S. in Biomedical Engineering as a UCLEADS scholar from the University of California in Irvine. His work is published in journals including Science and Lancet Hematology.


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