Kalistyn Burley

Kalistyn Burley has a diverse work experience in the field of computational and structural biology as well as protein formulation research. Kalistyn started their career as a Microbiology and Immunology Lab Assistant at Dartmouth Hitchcock Medical Center in 2007. Kalistyn then worked as a Life Sciences Research Assistant at Lawrence Berkeley National Laboratory, where they used molecular probes and fluorescence microscopy to detect chromosomal translocations and mutations.

In 2011, Kalistyn worked as a Laboratory Manager/Research Associate at UCSF Benioff Children's Hospital Oakland, where they characterized the structure of lipid-free apoA-I and managed student interns. Kalistyn also worked as a Machine Shop Lab Assistant and Biochemical Engineering Research Assistant at Thayer School of Engineering at Dartmouth, where they instructed students in the operation of machines, generated engineering drawings, and assisted in graduate research related to the glycosylation of mammalian proteins.

Kalistyn then joined BioMarin Pharmaceutical Inc. in 2014 as a Protein Formulation Research Associate, where they assisted in the development and assessment of protein, peptide, and small molecule formulations. Kalistyn evaluated the stability of biologic formulations through various assays.

In 2019, Kalistyn had an internship at Vertex Pharmaceuticals, where they developed a tool to visualize and evaluate electron density maps for CryoEM and X-ray structures of integral membrane proteins. Kalistyn also compiled a comprehensive database of integral membrane proteins in the Protein Data Bank and utilized MMTF technology for protein structure analysis.

From 2020 to 2021, they worked as a Research Scientist I, Computational Chemistry at Vertex Pharmaceuticals, focusing on computational chemistry research. Kalistyn then joined Neomorph, Inc. in 2021 as a Scientist II, Computational Chemistry, where they continued their work in computational chemistry until joining OpenEye, Cadence Molecular Sciences in 2023 as an Applications Scientist II.

In addition to their industry experience, Kalistyn pursued their Ph.D. in Computational Chemistry/Structural Biology at UC Irvine from 2015 to 2020. Kalistyn'sresearch focused on developing and validating mixed MD/non-equilibrium candidate Monte Carlo simulation methods to enhance sampling in molecular dynamics simulations.

Overall, Kalistyn Burley has a strong background in computational chemistry, structural biology, and protein formulation research, with experience in various roles and responsibilities throughout their career.

Kalistyn Burley pursued their education with dedication and passion. Starting in 2005, they attended Dartmouth College where they obtained their AB degree in Biomedical Engineering in 2009. Following this, they enrolled at UC Irvine in 2015 to pursue a Doctor of Philosophy - PhD in Pharmaceutical Sciences, which they successfully completed in 2020. By diligently studying these fields, Kalistyn Burley has equipped herself with in-depth knowledge and expertise in biomedical engineering and pharmaceutical sciences.