Parthenon Therapeutics
Prior to joining Parthenon as the Principal Scientist of Cancer Biology, Yan has over 10 years of experience in industry and academia. One of Yan's postdoctoral research published in Cell has a significant impact on advancing the mechanistic understanding of TGF-β signaling in the brain development, with an emphasis on microglia and immune function. She also played the key roles in conducting the preclinical studies on CTX-8371 to enable IND filing in Compass Therapeutics. Yan received postgraduate training at Harvard Medical School and Children's Hospital Boston in the laboratory of Dr. Timothy Springer and received a Ph. D from Chinese Academy of Sciences.
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Parthenon Therapeutics
Parthenon Therapeutics is inventing a novel class of anti-cancer therapies that reprogram the tumor microenvironment (TME). The interplay between cancer cells and their surrounding microenvironment is relevant in drug development as many cancers use the TME to build barriers that shield immune system attack. One approach, PRTH-101, breaks these barriers to overcome recalcitrant cancers. Based on rigorous, groundbreaking research, we are designing a portfolio of drug candidates to treat the right patients at the right time.