Dr. Cryer obtained his BA degree from Harvard College, Cambridge, Massachusetts, (1982) and his MD degree from Baylor College of Medicine (1986), where he also obtained his internal medicine residency training from 1986 to 1989. He obtained his gastroenterology fellowship training at the University of Texas Southwestern Medical Center at Dallas (1989 to 1992). Since completing his fellowship training in 1992, he has been a member of the gastroenterology faculty. He is active in the gastroenterology professional associations and was an Associate Chairman of the Esophagus, Stomach and Duodenum section of the American Gastroenterological Association from 1997 to 1999. Dr. Cryer’s clinical interests are in general gastroenterology. His specific areas of interest are acid-peptic diseases of the upper gastrointestinal tract. Specific disease states of interest are Helicobacter pylori-induced ulcer disease and nonsteroidal anti-inflammatory drug-induced ulcers. His primary research interest has been in the pathogenesis of peptic ulcer disease. His research focus has been clinically oriented in that he has exclusively studied the pathophysiology of these processes in humans. Recent investigations have explored the mechanism of gastrointestinal toxicity of nonsteroidal anti-inflammatory drugs within the stomach and duodenum. The most recent aspect of NSAID investigation has been an evaluation of the cyclooxygenase (COX)-2–specific NSAIDs. Another area of investigation has recently evaluated the effects of NSAIDs in gastroesophageal reflux disease.