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Wei-Jong Shia

Senior Principal Scientist at Polaris Pharmaceuticals

Wei-Jong Shia has a strong background in protein purification and analytics for biotherapeutic development, with a focus on cancer treatment. They began their career as a Graduate Student at The Pennsylvania State University, where they conducted research until 2006. Following that, they worked as a Postdoc Fellow at The Scripps Research Institute from 2006 to 2008, and then at the University of California, San Diego from 2008 to 2012. At Polaris Pharmaceuticals, Wei-Jong held various roles, including Research Scientist from 2012 to 2014, Senior Scientist from 2014 to 2015, Principal Scientist from 2016 to 2021, and currently serves as a Senior Principal Scientist. Their work at Polaris Pharmaceuticals focused on protein purification and analytics for the development of arginine-depleting biotherapeutic leads for cancer treatment, as well as the purification of other proteins for biotherapeutics discovery-stage projects.

Wei-Jong Shia earned a Ph.D. in Biochemistry, Microbiology, and Molecular Biology from Penn State University, where they studied from 2000 to 2006. Prior to that, they completed their undergraduate studies at National Sun Yat-Sen University, earning a Bachelor of Science (BS) degree in Biology from 1993 to 1997.

Location

San Diego, United States

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Polaris Pharmaceuticals

Polaris Group, a privately held multinational biopharmaceutical drug company, specializes in the research and development of protein drugs to treat cancer and other debilitating diseases in humans. Polaris' lead project is ADI-PEG 20, a biotherapeutic agent that is in advanced clinical development for the treatment of hepatocellular carcinoma and metastatic melanoma. Polaris is collaborating with EnzymeRx in the development of Uricase-PEG 20 for the treatment of gout, tumor lysis syndrome, and other diseases related to hyperuricemia. Polaris is also researching and developing other biotherapeutic agents and has a small molecule drug program. The latter utilizes a rational structure-based approach for the design of novel compounds that inhibit the biological function of cancer-related protein targets.