Dr. Shacham is a serial entrepreneur in the fields of Biotech and climate. Dr. Shacham is currently a co-founder and general partner at E44 Ventures, a new studio venture focused on partnering with academia and early ideators, to build technology-based companies to contribute to a cleaner, more sustainable future for the planet. Prior to that, Dr. Shacham founded Karyopharm Therapeutics (NASDAQ: KPTI) where she created the novel oral cancer drug Xpovio® , and led its development from idea to commercialization: Xpovio is now approved worldwide.
Current role