Dr. Paul Nioi, PhD, joined Alnylam in March 2018 and leads both the human genetics and translational research functions. Building upon his depth of prior experience, he has led the creation of the Alnylam Translational Genetics Center (ATGC), putting in place a capability that allows the deep mining of genotype-phenotype databases representing hundreds of thousands of individuals. Paul’s team applies these data to identify new drug targets and to gain important insights into disease trajectories to aid patient discovery efforts. His group is also responsible for advancing new liver and CNS RNAi therapeutics for a variety of diseases.
Alnylam has pioneered the translation of RNA interference from a Nobel Prize-winning discovery into a new class of approved medicines.
Prior to Alnylam, Paul spent 15 years in the biotech and pharmaceutical industries, including tenures at deCODE genetics, Amgen, and Schering-Plough.
Paul obtained his academic training at the University of Edinburgh (BSc) and the University of Dundee (PhD).