Matthews O. Bradley

Dr. Bradley has held key positions within the biopharmaceutical industry for 28 years and has extensive expertise in drug discovery and strategic drug development with a focus on target selection, drug proof of concept, preclinical pharmacology/toxicology, and IND/Phase I/II/III/NDA preparation in numerous therapeutic areas.

Prior to forming SAJE Pharma, Dr. Bradley ran his own consulting firm, working with small and mid-sized bio and pharmaceutical companies. He concentrated on developing strategic research and development plans for clients and on carrying out those plans using an extensive network of high quality, cost-efficient CROs.

Dr. Bradley has been the founder or co-founder of five previous biopharmaceutical companies where he has served in various executive R&D and board functions. Those companies include: Genetic MediSyn, Protarga, Replicon, Apothec, and Index Therapeutics. His work in those companies resulted in in-licenses, out-licenses, 18 patents, and numerous drugs discovered and developed through regulatory submissions.

Previously to these companies, Dr. Bradley worked for 12 years at Merck and Co., where he was Director of Safety Assessment and Biological Research. Before joining Merck, Dr. Bradley was a Senior Staff Fellow at the National Cancer Institute of the National Institutes of Health where he worked on cancer drug development. He has been involved in several worldwide regulatory submissions in the areas of allergy, neurology, infectious disease, cardiovascular disease, and oncology.

Dr. Bradley received a B.A. in Biology from The University of Pennsylvania and a Ph.D. in Biological Sciences from Stanford University. He was a Leukemia Society Postdoctoral Fellow at Stanford in the laboratory of Dr. Robert Schimke, where he studied molecular and cellular biology applied to mechanisms of aging and carcinogenesis. Dr. Bradley has authored 11 issued patents, 4 recent patent applications for GSNOR inhibitors, 70 peer-reviewed scientific publications, and numerous abstracts, book chapters, reviews, and published symposium conferences.