J Fraser Wright

Chief Technology Officer / Advisor at Sio Gene Therapies

J Fraser Wright has an extensive work experience in the field of gene therapy and biotechnology. J Fraser is currently a Professor of Pediatrics at Stanford University School of Medicine, where they focus on the advancement of gene-based medicines. In 2019, they also co-founded Kriya Therapeutics and serves as the Chief Scientific Advisor.

Prior to these roles, Wright established their own consulting firm called Wright Biologics Consulting in 2010, where they provided expertise in viral vector product chemistry, manufacturing, and controls. J Fraser was also the Chief Technology Officer/Advisor at Axovant Gene Therapies, Ltd in 2018.

Wright's significant contributions to the field can be traced back to their co-founding of Spark Therapeutics, Inc. in 2013. J Fraser played a crucial role in the establishment of the company as a leading gene therapy biotechnology firm, and led the technology transfer from The Children's Hospital of Philadelphia to Spark. J Fraser also participated in the company's IPO funding efforts.

Prior to Spark, Wright worked at the University of Pennsylvania School of Medicine as a Faculty Professor of Pathology and Laboratory Medicine. J Fraser focused on gene therapy vector design and optimization, and published numerous research articles, abstracts, and patents during their tenure.

Before joining the University of Pennsylvania, Wright established and directed The Children's Hospital of Philadelphia's Clinical Vector Core Facility. J Fraser was responsible for the development and manufacturing of gene therapy-based investigational products for clinical trials. J Fraser also worked as an investigator at the Children's Hospital of Philadelphia Research Institute.

Early in their career, Wright held positions at Avigen, where they directed the development and clinical manufacturing of recombinant AAV vectors, and at Sanofi Pasteur as a scientist.

Overall, J Fraser Wright has made significant contributions to the field of gene therapy and has a broad range of experience in various roles within academia, consulting, and industry.

J Fraser Wright pursued their education in the field of Biochemistry and Physiology. J Fraser completed their Bachelor of Science (B.Sc.) degree at the University of Toronto - University of Trinity College, with a duration from an unspecified year to 1983. Subsequently, they enrolled at the University of Toronto, where they pursued a Doctor of Philosophy (Ph.D.) degree in Biochemistry and Molecular Immunology. J Fraser successfully completed this program between the years 1983 and 1989.

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Timeline

  • Chief Technology Officer / Advisor

    May, 2018 - present