Mark is a computational biochemist, specializing in algorithms to search chemical space. His PhD thesis helped to establish molecular voxel theory (MVT), the algorithmic framework that Ten63 uses to search through unprecedentedly large sets of potential inhibitors. Moving on to an independent position, he developed algorithms to scale MVT up to the 100 trillion-molecule scale. Most recently, at Ten63, he has adapted these algorithms from protein to small molecule design, and continues to focus relentlessly on improving their usability, modeling accuracy, and computational efficiency.
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