Dr. Hirth co-founded and led Plexxikon, Inc. as its CEO as it built a novel, structure-guided drug discovery platform that advanced several new chemical entities into the clinic, including Zelboraf, which was FDA approved and led to the company’s 2011 acquisition by Daiichi Sankyo for $935 million. Prior to Plexxikon, Dr. Hirth was President of SUGEN, Inc., where he was instrumental in building the company from its inception as well as advancing several kinase inhibitors through clinical trials, including Sutent, which was FDA approved and led to the company’s 1999 acquisition by Pharmacia & Upjohn, Inc. for $728 million. Prior to SUGEN, Dr. Hirth was Vice President of Research at Boehringer Mannheim where he successfully led the company’s erythropoietin program to approval in 1989, which was sold under the name Recormon. Before moving into industry, Dr. Hirth was a research scientist with the Max Planck Institute following his post-doctoral work at University of California, San Diego and obtaining his PhD in molecular genetics from Heidelberg University, Germany.