Gary A. DeCrescenzo

SVP, Pharmaceutical Research & Development at Aclaris Therapeutics

Gary DeCrescenzo serves as Aclaris’ Senior Vice President, Pharmaceutical Research and Development, and has more than 30 years of experience in pharmaceutical research and development. His experience spans both discovery and early development, having led medicinal chemistry, chemical development, and pharmaceutical science units.

Prior to joining Aclaris, Gary served as Executive Director of Chemistry at BioMed Valley Discoveries, Inc., the translational sciences division of the Stowers Institute for Medical Research. He has also held multiple scientific and leadership positions at Pfizer and Pharmacia, including Executive Director of Medicinal Chemistry and Immunology & Inflammatory Diseases. Gary successfully led multiple programs from discovery through early clinical development across several therapeutic areas, including inflammation, cardiovascular, infectious diseases, and oncology. Over his career, Gary has focused on the inhibition of aspartyl and metalloproteases, kinases, chemokine, and nuclear hormone receptors. Gary has co-authored more than 30 peer-reviewed publications and is listed as co-inventor on more than 100 patents.

Gary received his Bachelor of Science in Chemistry and Master of Science in industrial chemistry from the University of Central Florida.

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