Cynata Therapeutics
Jolanta Airey MD is the Chief Medical Officer at Cynata Therapeutics, bringing a wealth of experience in providing medical expertise to clinical development programs to support product registration and marketing. With a background in various roles in pharmaceutical development and clinical research, Jolanta has a strong network with clinical investigators and key opinion leaders. Airey's experience ranges from serving as a Medical Director at BIOTA Pharmaceuticals to being an Associate Medical Director at Kendle International, LLC. Throughout their career, Jolanta has been involved in various therapeutic areas and worked on clinical trials in the Asia Pacific region as well as large multinational trials as a global medical monitor.
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Cynata Therapeutics
Cynata Therapeutics Limited (ASX: CYP) is an Australian clinical-stage stem cell and regenerative medicine company focused on the development of therapies based on Cymerus™, a proprietary therapeutic stem cell platform technology. Cymerus™ overcomes the challenges of other production methods by using induced pluripotent stem cells (iPSCs) and a precursor cell known as mesenchymoangioblast (MCA) to achieve economic manufacture of cell therapy products, including mesenchymal stem cells (MSCs), at commercial scale without the limitation of multiple donors. Cynata’s lead product candidate CYP-001 met all clinical endpoints and demonstrated positive safety and efficacy data for the treatment of steroid-resistant acute graft-versus-host disease (GvHD) in a Phase 1 trial. Clinical trials of Cymerus MSC products in osteoarthritis (Phase 3) and in severe complications arising from COVID-19 (Phase 2) are currently ongoing. Planning is also underway for further clinical trials of Cymerus MSC products in GvHD (through licensee Fujifilm), critical limb ischemia, idiopathic pulmonary fibrosis, renal transplantation, and diabetic foot ulcers. In addition, Cynata has demonstrated utility of its Cymerus MSC technology in preclinical models of numerous diseases, including the clinical targets mentioned above, as well as asthma, heart attack, sepsis, acute respiratory distress syndrome (ARDS) and cytokine release syndrome.