Joseph Dukes

Joe joined Enara Bio in 2019 following leadership across research and early development of novel immunotherapies, having led molecules from early discovery and validation through to first-in-human clinical studies.

Prior to joining Enara Bio, Joe spent eight years at Immunocore, developing novel TCR-based bispecific therapeutics. During this time, he established a bespoke, in vitro preclinical approach for generating safety data to de-risk TCR-based therapeutics. In his role as Head of Biology, Joe oversaw TCR discovery, characterisation, and preclinical screening of drug candidates. In addition, Joe was Program Leader for the second TCR-bispecific molecule to enter the clinic, leading cross-functional teams from early discovery in research, through preclinical and clinical development to successful IND/CTA submissions and first-in-human Phase 1 studies.

Joe obtained a PhD in Cell Biology and a subsequent post-doctoral fellowship at The University of Bath.