Anthony Mannion, Ph.D.

Anthony Mannion, Ph.D., has a strong background in microbiome research and immunology. Anthony started their career at Massachusetts Institute of Technology (MIT) Division of Comparative Medicine (DCM) in 2013 as a Ph.D. researcher, focusing on investigating the association and pathogenic potential of a novel gastrointestinal Helicobacter species to cause inflammatory bowel disease (IBD) and colon cancer. During this time, they discovered, isolated, and characterized novel bacterial cytotoxins and genotoxins.

After completing their Ph.D., they continued their research at MIT's DCM as a Postdoctoral Researcher from 2018 to 2021. In this role, they investigated infectious agents and host-microbiome interactions associated with inflammatory diseases and cancers of the gastrointestinal tract. Anthony developed and performed molecular and cell culture assays to identify and characterize microbial virulence factors and host responses. Anthony also utilized animal models to study host immune responses under different conditions.

In 2021, Anthony Mannion joined Evelo Biosciences as a Senior Scientist. In this role, they are responsible for researching, selecting, and developing microbe and extracellular vesicle (EV) products for peripheral anti-inflammatory and immunomodulatory pharmacology via the gut-immune axis. Anthony is leading an interdisciplinary analytical strategy group to increase product understanding and designing and executing experiments to isolate and identify bioactive ligands from microbes and EVs. Anthony'swork at Evelo Biosciences has advanced the identification of critical structures driving mechanism of action (MoA).

Overall, Anthony Mannion's work experience demonstrates their expertise in microbiome research, investigating host-microbiome interactions, and identifying novel bacterial factors in inflammatory diseases and cancers.

Anthony Mannion, Ph.D. began their education journey in 2010 at Massachusetts College of Pharmacy and Health Sciences, where they received their Bachelor's Degree in Pharmacology and Toxicology in 2014. Anthony then pursued a Master's Degree in Pharmacology at Northeastern University from 2014 to 2016. Following this, they attended Northeastern University again and obtained their Doctor of Philosophy (Ph.D.) in Pharmaceutical Sciences and Biomedical Sciences between 2016 and 2018. Recently, from 2018 to 2021, Anthony Mannion completed their Postdoctoral Researcher stint in the James G. Fox Lab at the prestigious Massachusetts Institute of Technology.