Maria Hackett

Maria Hackett has extensive experience in the biotech and pharmaceutical industry, with a focus on target validation, lead optimization, and therapeutic program advancement. Maria is currently working as a Senior Scientist at EvolveImmune Therapeutics, where they support the development of CD3-bispecific antibodies for the treatment of solid tumors and hematologic cancers. Maria'sresponsibilities include performing biochemical and biophysical assays, evaluating binding and stability, and conducting tumor killing assays.

Prior to their current role, Maria worked as a Biotech Consultant at AlphaSights, providing insight and analysis to clients on drug discovery and development opportunities. Maria also has experience as a Senior Scientist at Cue Biopharma, where they demonstrated the functional binding of novel biologics and confirmed target engagement in therapeutic programs.

Before Cue Biopharma, Maria worked as a Research Scientist at Bayer, focusing on developing assays to characterize receptor binding of insecticidal toxins. Maria utilized rational design and directed evolution strategies to investigate pore-forming toxin mode of action. Maria also worked as a Scientist at Aileron Therapeutics, conducting MOA studies and analyzing protein interactions for stapled peptides as novel therapeutics.

Maria's early experience includes working as a Scientist at Novartis Institutes for BioMedical Research, producing recombinant GPCRs to support crystallography efforts and successfully expressing multiple GPCRs and ligands in E. coli.

Overall, Maria Hackett has a strong background in biotech research, with expertise in target validation, assay development, mechanism of action studies, and protein-protein interactions.

Maria Hackett earned a Certificate in Project Management from Georgetown University in the academic year 2020-2021. Prior to that, they obtained a Master's Degree in Microbiology and a Bachelor's Degree in Biology from the University of New Hampshire. No specific start or end years were provided for their degrees at the University of New Hampshire.