Executive Director, Structural Biology

About Us

Exscientia is an AI-driven pharmatech company committed to discovering, designing and developing the best possible drugs in the fastest and most effective manner. Exscientia developed the first-ever functional precision oncology platform to successfully guide treatment selection and improve patient outcomes in a prospective interventional clinical study, as well as to progress AI-designed small molecules into the clinical setting.

Our pipeline demonstrates our ability to rapidly translate scientific concepts into precision-designed therapeutic candidates, with more than 15 projects underway. By designing better drugs, faster, we believe the best ideas of science can rapidly become the best medicines for patients.

The Role

As the Head of Structural Biology you will have the opportunity to lead a high-performing team and drive the growth of our structure-based design capabilities across drug discovery portfolios. Working at the intersection of experimental structural biology, drug design, AI, physics, and informatics, you will be responsible for building technical solutions that increase the quality and efficiency of our design capability.

Please note this is a UK-based hybrid role and regular travel is required to our offices in Oxford, UK (approximately 2-3 days per week), with flexibility to work from home the remaining time. We are a flexible working organisation and we’re willing to consider other options which would provide similar contact time with the team.

You will have the opportunity to:

• Design industry leading strategies which enable structure-based design and the development of molecules to advance our drug discovery portfolio.
• Utilise the latest advances in AI and experimental techniques to drive drug discovery programs and automate our approach to generate structures and accelerate structural insights.
• Lead a small team of talented Structural Biologists (X-ray crystallography and cryo-EM) and foster a positive work environment that supports team growth.
• Collaborate with our team of drug designers and AI/ML data scientists to enhance our structure-based design methods.
• Manage structural biology resources and develop and implement strategies to deliver on portfolios.
• Take an active role in target/tractability assessment and hit finding activities, especially fragment-based lead discovery.
• Communicate and evangelise by sharing your work through internal and external presentations, conferences, or scientific publications, actively promoting our innovative approach.