Stephen Frye

Dr. Frye is Fred Eshelman Distinguished Professor and co-director of the Center for Integrative Chemical Biology and Drug Discovery (CICBDD) at the University of North Carolina (UNC) at Chapel Hill. He additionally co-directs the Molecular Therapeutics program in the Lineberger Comprehensive Cancer Center. Through the CICBDD, Dr. Frye has helped foster numerous collaborative academic drug discovery projects, including one program progressing through multiple clinical trials. In addition, his Center has established a leading program in the area of chemical biology of chromatin regulation and Dr. Frye has published more than 70 papers in this field.

Prior to joining UNC, Dr. Frye was the worldwide vice president of Discovery Medicinal Chemistry at GlaxoSmithKline (GSK) where he managed five departments and more than 200 chemists in the U.S. and U.K. developing global protein target-class chemical science. During his 20-year career at GSK, the teams led by Dr. Frye successfully developed three FDA approved drugs: Avodart, Tykerb and Pazopanib. He has a Ph.D. in Organic Chemistry from UNC and a B.S. in Chemistry from North Carolina State University.