Tzu-Yi Yang

Senior Scientist at Frontier Medicines

Tzu-Yi Yang's work experience includes roles at Frontier Medicines, Harvard Medical School and Massachusetts General Hospital, the Center for Mass Spectrometry and Proteomics at the University of Minnesota, the University of Minnesota, Purdue University, National Taiwan University, and the Taiwan Forestry Research Institution.

At Frontier Medicines, Tzu-Yi Yang is currently working as a Senior Scientist.

At Harvard Medical School and Massachusetts General Hospital, Tzu-Yi Yang worked as a Research Scientist. In this role, they led a team in discovering and characterizing ligandable cysteines using activity-based protein profiling (ABPP). They also established a proteomics program and developed a pipeline for mass spectrometry-based ABPP, among other responsibilities.

At the Center for Mass Spectrometry and Proteomics at the University of Minnesota, Tzu-Yi Yang worked as a Researcher 5. They assisted university researchers with experimental design and data analysis, established pipelines for scheduled parallel reaction monitoring (PRM) and data independent acquisition (DIA), and operated various mass spectrometry equipment.

At the University of Minnesota, Tzu-Yi Yang worked as a Postdoctoral Associate. They led a team in investigating the specificity and selectivity of peptide biosensors in human cells and developed methods for detecting phosphorylation using mass spectrometry.

At Purdue University, Tzu-Yi Yang worked as a Graduate Student and later as an Instructor. As a graduate student, they developed quantitative mass spectrometry methods to measure phosphorylation levels in leukemia clinical samples and examined phosphorylation in Abl and Lyn protein kinases. As an instructor, they taught high school students and assisted with teaching assistant duties.

At National Taiwan University, Tzu-Yi Yang worked as an Undergraduate Research Assistant, supporting investigations on the interaction between Grb7 and FAK.

At the Taiwan Forestry Research Institution, Tzu-Yi Yang worked as an Intern and identified a gene in the paclitaxel biosynthetic pathway in Taiwanese Yew.

Overall, Tzu-Yi Yang has extensive experience in protein profiling, proteomics, mass spectrometry, and peptide synthesis, with a focus on investigating protein interactions and phosphorylation.

Tzu-Yi Yang pursued their Doctor of Philosophy (Ph.D.) from 2008 to 2014 at Purdue University, specifically in the Purdue University Interdisciplinary Life Science Program (PULSe) within the Department of Medicinal Chemistry and Molecular Pharmacology. Prior to that, they completed their Bachelor of Science (B.S.) degree in Plant Pathology and Microbiology from National Taiwan University from 2003 to 2007.

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Timeline

  • Senior Scientist

    September, 2022 - present

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