Ana Castano, M.D. has a long and distinguished career in the medical field. Ana began their career in 2003 as a Postdoctoral Research Fellow at Harvard Medical School/BWH, where they investigated the systemic immunological response and therapeutic impact of intravenous injection of mesenchymal stem cells (MSC) in a mouse model of sepsis. Ana then moved on to Harvard Medical School/BWH as a Postdoctoral Research Fellow, where they studied the immunological basis of renal fibrosis and the role of Fc gamma receptors and Pentraxins in its physiopathology. In 2013, they became a Researcher at the Massachusetts Institute of Technology (MIT)/Synthetic Biology Center, where they constructed Synthetic amplified RNA (SafeR) circuits for “smart vaccination.” In 2015, they were hired as a Senior Research Scientist at Massachusetts General Hospital, where they designed next generation genetically modified chimeric antigen receptor (CAR) T cells as immunotherapy in patients with cancer. In 2019, they joined Elicio Therapeutics as an Associate Principal Scientist - Cell Therapy Program, where they independently and collaboratively developed strategic goals for advancing preclinical research efforts in adoptive cellular therapy applications of Chimeric Antigen Receptors (CARs) and T Cell Receptor T cells (TCR-Ts) to treat blood and solid tumors. Ana also contributed to the conception, planning, and execution of cellular therapy research strategy in combination with amphiphile vaccine platform. In 2022, they moved to Garuda Therapeutics as a Principal Scientist and to Carmine Therapeutics as a Principal Scientist.
Ana Castano, M.D. obtained their Doctor of Medicine (MD) from Pontificia Universidad Javeriana. In 2007, they also obtained certification from the Educational Commission for Foreign Medical Graduates (ECFMG). In 2012, they completed courses at Harvard Medical School, Harvard University, and Harvard Extension School, including Introduction to Translational Medicine, Principles and Techniques of Molecular Biology, Graduate Research Methods and Scholarly Writing in Biotechnology, and Professional Writing Workshop.
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