Wade Harper is a seasoned cellular biologist whose research is focused on the analysis of ubiquitin-driven signaling systems and the integration of quantitative proteomics and cell biology to understand the mechanism for the signaling systems.
Wade is the Bert and Natalie Vallee Professor of Molecular Pathology and Chairman of the Department of Cell Biology at Harvard Medical School, and co-Director of the Dana Farber-Harvard Cancer Center Cancer Cell Biology Program. His lab has used proteomic approaches to define the interaction networks of various protein families (deubiquitinating enzymes, F-box proteins) and signaling networks (autophagy, ERAD, CRLs, Parkin), as well as to define the ubiquitin-modified proteome.
Wade has received many awards, including the American Cancer Society Junior Faculty Award, the Michael DeBakey Award for Excellence in Research in both 1994 and 2000, and the Javits award from the National Institute of Health. Wade received his doctorate in chemistry at the Georgia Institute of Technology prior to completing postdoctoral studies in biological chemistry at Harvard Medical School.