Scientist II Or Senior Scientist, Immunology

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on delivering oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Kymera is also progressing degrader oncology programs that target undrugged or poorly drugged proteins to create new ways to fight cancer. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How you’ll contribute:

• Independently design and execute on cellular assay strategy to support indication selection and expansion of lead optimization program
• Develop cytokine release, proliferation and differentiation immune cell assays using healthy and diseased samples, with a focus on B cells and monocytes
• Profile innate and adaptive immune cells by flow cytometry multi-plex assays
• Independently analyze and present findings at group and project team meetings

What skills and experience you’ll bring:

• Extensive hands-on experience with isolation and culture of primary immune cells
• Must have experience with developing flow multi-plex panels to identify immune subsets (both human and mouse a plus) and other immunoassays such as ELISAs
• A plus if familiar with immune cellular assays such as M1 macrophage polarization, B cell differentiation and Ig class switching assays
• Ability to summarize literature findings to support scientific and technical strategies
• Experience with software such as flowjo and graphpad prism
• Attention to detail and proven track record in handling, analyzing and recording experimental data

Skills and experience not an exact match?:

Go ahead and submit your resume (and a cover letter, if you’d like!).  If this role isn't right for you, we can keep you in mind for future opportunities.

                                                                                                                                                                                  

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.