Lion TCR
Prof Antonio Bertoletti is named top 0.1% Hepatitis B Expert in the World over the past 10 years (Expertscape in 2019). He was the Director of Infection and Immunity Program at the Singapore Institute for Clinical Sciences (SICS) under A*STAR until 2013. Currently, he is a professor in the Division Emerging Infectious Diseases at Duke-NUS Graduate Medical School. Prof Antonio was trained as a specialist in Infectious Diseases and has always been interested in immunological control of persistent viral infections, particularly Hepatitis B (HBV). His current research focuses on the development of new immunological based therapies (TCR-redirected T cells, HLA-peptide specific antibodies) for the treatment of HBV and Hepatocellular carcinoma (HCC), and the characterization of human intra-sinusoidal hepatic immune system. Prof Antonio and his team have received the 1st Prize Award based on the first in the world using HBV-specific TCR-T for liver cancer. He has been holding scientific advisor role for Gilead, MedImmune, Vir Biotechnology and Janssen.
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