E-Ching Ong

Senior Scientist, Process Development at Lyell Immunopharma

E-Ching Ong, PhD has a diverse work experience in the field of process development, with a focus on cell therapies and gene editing. E-Ching started their career at the University of Oklahoma Health Sciences Center, where they served as a Graduate Research Assistant, conducting research on intracellular calcium signaling pathways and their role in maintaining adult bone homeostasis through osteoclastogenesis.

Following their graduate work, E-Ching Ong became a Fellow at the University of Oklahoma Health Sciences Center, continuing their research on the mechanisms by which MyoD family inhibitors inhibit transient receptor potential channels during osteoclastogenesis.

In 2013, they joined the Oklahoma Medical Research Foundation as a Postdoctoral Research Fellow, where they studied the role of epigenetics in the development of blood vessels and focused on identifying genes essential for vascular development. E-Ching also established pathological mouse models to examine the role of specific enzymes in maintaining postnatal vascular integrity.

In 2015, E-Ching Ong moved to Just Biotherapeutics, where they worked as a Postdoctoral Fellow in Process Design. E-Ching contributed to the development of an inducible expression system that improved productivity in stable CHO cell pools. E-Ching also designed and implemented an in-house vector system to shorten the generation of stable cell pools and utilized automation and robotics to streamline routine tasks.

In 2018, they joined Universal Cells as a Scientist, focusing on process development for clinical-grade iPSC culture and gene editing using rAAV vectors to generate off-the-shelf cell therapies.

Most recently, E-Ching Ong joined Lyell Immunopharma in 2020. E-Ching initially held the position of Scientist in the Process Development team and later advanced to Scientist II. Currently, they serve as a Senior Scientist, contributing their expertise in process development.

Overall, E-Ching Ong has a strong background in process development and has made significant contributions to the field through their research and industry experience.

E-Ching Ong, PhD, earned a Bachelor of Science (BS) degree in Biochemistry and Molecular Biology from Michigan State University from 2002 to 2004. Following this, they pursued a Doctor of Philosophy (Ph.D.) in Cell Biology at the University of Oklahoma from 2006 to 2011.

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