Dr. Jacobsen joined AstraZeneca, Neuroscience iMed as Senior Project Director in December 2012, from Proteostasis Therapeutics, a drug development startup, where he was Vice President, Head of Translational Biology Department for two years. He has extensive drug development experience in the pharmaceutical industry, with focus on neurodegeneration and the targeting of misfolded proteins, having been Senior Research Fellow, Neuroscience Translation at Pfizer Global R&D, and Associate Director and Team Leader, Alzheime’s disease-Modifying Program at Wyeth Research. Prior to that, Dr.Jacobsen was a Senior Scientist in CNS Biology, Lederle Labs, American Cyanamid. In addition, he serves on the Scientific Advisory Boards of several biotechnology startup organizations, and is adjunct Associate Professor at New York University School of Medicine.