Dr. Seki is currently conducting his basic and translational research focusing on matrix-mediated liver fibrosis, alcoholic and nonalcoholic fatty liver disease, and liver malignancy at Cedars-Sinai Medical Center. Dr. Seki’s expertise lies in the field of liver immunology, and basic and translational gastroenterology and hepatology research. The research team has expertise in using genetically modified animals and isolation of primary cultured liver cells including hepatocytes, Kupffer cells, and hepatic stellate cells. Dr. Seki was trained as a GI-hepatobiliary surgery in Japan. After his clinical training, Dr. Seki started his research career studying liver immunology including Toll-like receptor signaling and inflammasome activation. In his postdoctoral training at Columbia University, he studied the role of TLR4 signaling in liver fibrosis.
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