Oxford SimCell Ltd
Joseph Kennerley is a seasoned professional in the biotechnology and engineering sectors, currently serving as Chief Scientific Officer at Oxford SimCell Ltd, where innovative genome-free bacterial biotechnology is being developed for healthcare applications. Joseph's academic credentials include a DPhil in Engineering Science from the University of Oxford and dual Bachelor's degrees in Chemical and Biological Engineering and Biochemistry and Molecular Biology from The University of Queensland. Previous roles encompass Quality Manager at Oxsed, Biotechnologist at Oxford BioMedica, and Process Engineer at Caltex Australia Petroleum Pty Ltd., among others. Joseph has also contributed to academia as a tutor at The University of Queensland and has research experience across various institutes focusing on cutting-edge topics in tissue engineering, microfluidics, and synthetic biology.
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Oxford SimCell Ltd
Oxford SimCell Ltd. is a biotechnology company using a novel inactivation method to manufacture genome-free bacterial cells with broad applications in the healthcare sector. The SimCell® technology platform gives us the power to use engineered bacteria in vivo without the possibility of growth, enabling new and effective ways to safeguard human health. SimCell® technology was developed at the University of Oxford and is exclusively licensed to Oxford SimCell Ltd. Please contact us for more information about our platform and its applications. SimCells® are genome-free, non-replicating bacteria produced by expressing a homing endonuclease within host cells, which enzymatically cleaves multiple restriction sites within the genome. This process completely halts cell division while preserving other key cellular features, making SimCells® useful for in vivo and in vitro applications that would be impossible with dividing cells. Existing chemical and irradiative bacterial inactivation technologies can be damaging to the cell. SimCells® are completely replication-deficient yet remain undamaged by our enzymatic genome-removal process, making them both safe and efficacious for use in situations where biocontainment is key. Manufacturing is a core competency at Oxford SimCell. Our production workflow lets us provide pure, high-quality SimCells® engineered for varied healthcare applications. SimCells® are stable, streamlined, bacterial chassis offering all the complexity and capability of whole cells in a safe, simplified form.