Yuxin W. has an extensive work experience in the field of pharmacology and scientific research. They are currently working as the Senior Director and Head of In Vivo Pharmacology at PAQ Therapeutics since May 2021. Prior to that, Yuxin held the position of Senior Director at WuXi AppTec from August 2018.
In 2018, Yuxin was the Senior Director and Head of Oncology Scientific Operations at Crown Bioscience, Inc. This role lasted from November 2018 to July 2019.
Before joining Crown Bioscience, Inc., Yuxin worked at Boston Biomedical (Sumitomo Dainippon Pharma Global Oncology) as a Senior Research Investigator and Director. In this role, Yuxin led the translational pharmacology group and established a translational platform to evaluate the mechanism of action (MoA) of small molecule oncology drugs. Yuxin also supported early stage drug development by confirming the MoA of multiple small molecular drugs in phase I and II clinical trials. This role lasted from November 2015 to November 2018.
From June 2011 to November 2015, Yuxin worked at Vertex Pharmaceuticals as part of the In Vivo Pharmacology team. During this time, Yuxin contributed to establishing patient derived animal models and supported the development and biomarker discovery of small molecule drugs for radiation/chemo sensitization projects.
Yuxin's career began in 2005 at Pfizer, where they worked as a Senior Scientist. In this role, they established animal models for metabolic disease target validation and performed in vivo studies for an oligonucleotide drug. Yuxin also developed high throughput assays for PK/PD and biomarker solutions, and identified a new drug target for HCC through siRNA screening. This role lasted from December 2005 to July 2011.
Prior to joining Pfizer, Yuxin worked as a Postdoctoral Research Scientist at Johns Hopkins Medical School from September 2002 to September 2005. During this time, they conducted global analysis of kinase activity, purified human proteins, and performed kinase activity assays on a human proteome microarray. Yuxin also collaborated with bioinformatics to build a kinase signaling network and conducted kinase specific inhibitor screening.
Yuxin's career began in academia as an Assistant Professor at Shandong University from September 1992 to July 1996.
Yuxin W. completed a Postgraduate Degree in Pharmacology at The Johns Hopkins University School of Medicine from 2002 to 2005. Prior to that, from 1998 to 2002, they pursued a Doctor of Philosophy (Ph.D.) in Pharmacology at the University of Alberta. In 1996 and 1998, Yuxin W. obtained a Master's Degree in Chemical Engineering from The Hong Kong University of Science and Technology. They also hold a Master's degree in Microbiology and Immunology, earned from Shandong University between 1989 and 1992. Additionally, Yuxin W. has publications and has been associated with The Johns Hopkins University School of Medicine, but the specific details regarding the degrees and field of study for these affiliations are not provided.
May, 2021 - present