Mary Beth Delena

Mary Beth DeLena is Chief Legal Officer at Paragon. She most recently served as General Counsel and Secretary at PepGen, Inc., a clinical-stage biotechnology company advancing the next generation of oligonucleotide therapies. Prior to that, Mary Beth spent 15 years at Alnylam Pharmaceuticals, where she held roles of increasing responsibility, including Senior Vice President, Deputy General Counsel, and Assistant Secretary. During her tenure, she played a pivotal role in Alnylam’s growth and success, supporting expansion from approximately 125 employees to over 2,000; leading a legal team that grew to over 40 professionals in multiple countries; and advising on strategic collaborations, licensing transactions, and capital-raising initiatives resulting in over $2.25 billion in proceeds. Mary Beth’s expertise spans securities law, corporate governance, research and development, risk management, compliance, insurance, labor and employment law, and executive compensation. Previously, she served as Vice President, Legal, and Secretary at Praecis Pharmaceuticals, establishing and managing the corporate legal function. She started her legal career as a Corporate Associate in the Boston office of Skadden, Arps, Slate, Meagher & Flom LLP. Mary Beth received her Juris Doctor from Northeastern University School of Law and her Bachelor of Arts in English from Trinity College.