Prime Medicine
Jacob Stewart-Ornstein has worked in various roles in the field of biology and computational science. Jacob is currently the Associate Director of Off-Target Biology at Prime Medicine, Inc. since October 2021. Prior to that, they served as an Assistant Professor in the Department of Computational and Systems Biology at the University of Pittsburgh from November 2018 to October 2021. Before joining the University of Pittsburgh, they were a Postdoctoral Fellow at Harvard Medical School from January 2013 to September 2018.
Jacob Stewart-Ornstein pursued their education at the University of California, San Francisco from 2007 to 2012. During this time, they obtained a PhD in Biochemistry and Molecular Biology.
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Prime Medicine
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Prime Medicine was founded to bring the promise of gene editing to patients. We use Prime Editing, a next-generation technology that can “search and replace” to restore normal genetic function almost anywhere in the genome. Prime Editing searches to find the precise place in the genome to edit and replaces the segment of faulty DNA with a correct copy of DNA. A single Prime Editor can correct the individual mutations found across patients, meaning Prime Editing can potentially address more than 90 percent of known disease-causing genetic mutations. We envision a world where this technology can cure, halt, and ultimately prevent genetic diseases, providing lifelong benefit to patients. Prime Medicine offers the opportunity to shape the future of gene editing and transform how medicines are used to treat disease. Realizing the promise of Prime Editing requires a talented team with diversity of viewpoints and expertise. We’re building a group of dedicated, scientifically curious individuals who are passionate about helping patients live longer, healthier lives.