Shoreline Biosciences
Research in Dr. Paust’s laboratory at the Scripps Research Institute seeks to elucidate the molecular mechanisms causal to murine and human NK cell-mediated adaptive immunity. Our long-term goal is to use this knowledge to develop novel anti-viral and anti-tumor vaccines or NK cell-based infusion products. Approaches include cell biology, molecular biology, and immunology experiments in mice, humanized mice, and using human specimens.
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Shoreline Biosciences
Shoreline's proprietary cell therapy technology platform is based on deep expertise in iPSC differentiation methods and genetic programming of the IL-15/CISH pathway for enhanced metabolic fitness and persistence of the engineered NK Cells to improve anti-cancer activity.