Simone Rauch has worked in a variety of roles in the field of science since 2013. Simone began their career as an Undergraduate Research Assistant at Boston University, where they developed a sensitive luciferase reporter gene assay to study the dynamics of artemin-induced RET signaling. After graduating in 2015, they pursued a PhD Candidate role at the University of Chicago, where they engineered programmable Cas13-based RNA-targeting proteins to study chemical RNA modifications site- and transcript-specifically, and developed a small and fully humanized CRISPR/Cas-inspired RNA-targeting systems (CIRTS) to study RNA regulatory proteins and control gene expression on transcripts of interest for potential future gene therapy applications. In 2020, Rauch joined Skyhawk Therapeutics as a Scientist I and Scientist II, where they developed a small molecule-inducible CIRTS for temporal control of RNA editing, translation, and degradation in cells and in vivo.
Simone Rauch began their educational journey in 2011 at Boston University, where they earned a Bachelor's Degree in Honors in Chemistry: Biochemistry. Simone then went on to the University of Chicago in 2015, where they earned a Master of Science in Biochemistry and Molecular Biology and a Doctor of Philosophy (Ph.D.) in Biochemistry and Molecular Biophysics in 2020.
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