Matthew Call

Matthew Call's research group led cooperatively by Dr. Melissa Call, investigates how immune cells respond to external cues that control immune responses. Cells are enclosed in a thin fatty membrane. This is essential for compartmentalizing chemical processes inside the cell but poses a formidable barrier to the passage of information between the inside and outside of the cell.

Matthew studied the molecular structures and mechanisms used by sensors on the cell surface to pass information across this barrier. They aim to understand these communication pathways and identify new ways to therapeutically manipulate immune responses in cancer, infection, and autoimmune diseases.