Sofia de Achaval

VP, Development at Tvardi Therapeutics

Sofia de Achaval, M.S., Ph.D. oversees the chemistry, manufacturing and controls and clinical operations at Tvardi. She has 10+ years of experience in clinical research spanning multiple indications including oncology and inflammation. During her time at The University of Texas MD Anderson Cancer Center she has had integral roles establishing basic, translational, and clinical research collaborations within and outside of the institution. For those collaborations she was responsible for regulatory and compliance, clinical research, and data management teams. Dr. de Achaval led the development of the IND of TTI-101 in cancer and spearheaded the planning and initiation of the first-in-man Phase 1 studies. She holds Master of Science and Doctor of Philosophy degrees in public health – epidemiology from The University of Texas Health Science Center, School of Public Health and BS in Biology from Texas A&M University.

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Tvardi Therapeutics

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Tvardi Therapeutics is a clinical stage, private biotechnology company developing a new class of breakthrough medicines for diverse cancers, chronic inflammatory diseases and fibrotic diseases. Founded in 2017 and based in Houston, Texas, the company is led by experienced entrepreneurs, innovative scientists and dedicated physicians.


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