Michael Knowles

​Dr. Michael Knowles is a Professor of Pulmonary and Critical Care Medicine at UNC-Chapel Hill. Dr. Knowles specializes in Genetic Modifiers of Disease phenotype in Cystic Fibrosis lung and liver disease, and is currently heading two multicenter studies: 1) Genetic Modifiers of Disease phenotype in CF lung and liver disease, which includes an International Consortium doing a whole-genome scan; and 2) a Consortium with eight sites in North America studying rare genetic disorders of mucociliary clearance. He received a BA and an MD from UNC-Chapel Hill and has over 30 years of clinical trial experience in the private and academic sectors with an emphasis on the following areas of study: biology, physiology, and clinical trials design. Dr. Knowles has been peer-selected for the 2017-2018 “The Best Doctors in America” award.