Aegle’s research team is headed by Dr. Badiavas—a board certified dermatologist and dermatopathologist—whose research has been focused on wound healing, bone marrow, stem cells, bioengineered skin, dermatology, and translational research for more than 30 years. Dr. Badiavas was among the first to describe the trafficking and engraftment of bone marrow cells to wounded skin, and the restoration of skin structures by bone marrow stem cells. He has been the principal investigator on protocols delivering stem cells to wounds for more than 15 years and was the first to describe the delivery of bone marrow stem cells to chronic wounds in humans. Dr. Badiavas has been awarded three IND’s by the FDA for the delivery of stem cells to patients. Having worked in this area for years, he is well versed in all recent regulatory aspects of cell-based therapeutics. His expertise in bone marrow stem cells began as a graduate student in 1982 when he worked on erythroid progenitors under the direction of Alan Erslev, Jaimie Caro and Hideko Kaji. Since then, Dr. Badiavas has completed his PhD, postdoctoral training, medical school, dermatology residency, and dermatopathology fellowship. He is a practicing dermatologist and dermatolopathologist with more than 20 years experience with particular interests in the histologic evaluation of wounds. He has been working with bioengineered skin materials for more than 25 years and has described several key histological features associated with the application of these materials to patients. Dr. Badiavas has also published and presented his findings in several preclinical studies for wounds including rodent and pig models. He has served as a consultant, NIH study section member, and moderator for wound based and stem cell projects. Dr. Badiavas has an extensive and diverse history of close collaboration with several highly regarded stem cell, bone marrow, and wound healing investigators. His unique training and experience allows him to comfortably move between these sometimes-distinct fields.
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