Ambys Medicines
Yury Popov, M.D., Ph.D. has a major research focus on liver fibrosis/cirrhosis. Specifically, he is investigating the basic mechanisms of progression and regression of liver scarring. His laboratory develops non-invasive diagnostic tools to measure these processes in the clinic, and novel therapies to prevent and reverse cirrhosis and its life-threatening complications. He is actively working on the development, validation, and optimization of small animal models for novel drug target discovery and efficacy testing. Some of his current basic research projects include the investigation of a novel macrophage-mediated pathway of fibrosis reversal and elucidating the molecular mechanisms of fibrotic matrix stabilization and collagen cross-linking which make liver scarring irreversible.
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Ambys Medicines
Ambys Medicines is a biotechnology company focused on discovering and developing regenerative and restorative therapies for people with advanced liver disease. Founded by world-renowned experts in liver disease and regenerative medicine, Ambys is pioneering the application of novel modalities including cell and gene therapy, and gain-of-function drug therapy, to meet the urgent need for treatments that have the potential to restore liver function and prevent the progression to liver failure across multiple liver diseases that are untreatable or poorly treated today.