Dr. Terhorst is Chief of Immunology at the Beth Israel Deaconess Medical Center of Harvard Medical School. Dr. Terhorst’s laboratory is interested in the assembly and signal transduction of the T cell receptor for antigen. They examine the role of the CD3 genes in thymocyte development and in T cell function in mice in which the CD3 genes have been eliminated by homologous recombination techniques. In addition, the mechanisms that govern expression of the three CD3 genes in early T cells are being studied. Dr. Terhorst received his PhD degree in molecular biology from the University of Leiden, The Netherlands.