David Holtzman

Dr. Holtzman is a Scientific Co-Founding Member of C₂N Diagnostics. Dr. Holtzman is an international authority in the field of Alzheimer’s Disease. He is the Andrew B. and Gretchen P. Jones Professor of Neurology and Developmental Biology at Washington University School of Medicine (WUSM). He is also head of WUSM’s Department of Neurology, the Associate Director of the institution’s Alzheimer's Disease Research Center, and Co-Director of the Hope Center for Protein Aggregation and Neurodegeneration. A major focus of Dr. Holtzman’s research is in understanding basic mechanisms underlying acute and chronic cell dysfunction in the CNS, particularly as these mechanisms may relate to Alzheimer’s disease and injury to the developing brain. Dr. Holtzman attended the Honors Program in Medical Education at Northwestern University receiving his B.S. (1983) and M.D. (1985). He completed his medical internship followed by Neurology residency at UCSF from 1985-1989. He then pursued post-doctoral research training in the lab of William C. Mobley, MD, PhD, at UCSF from 1989-1994. Also at UCSF, Dr. Holtzman established the Memory and Cognitive Disorders Clinic and was an Assistant Professor from 1991-1994. He moved to his own laboratory at WUSM in December of 1994. He was named as the Associate Professor of Neurology in 2001, Professor in November of 2002, and as the Andrew and Gretchen Jones Professor and Head of the Department of Neurology in October 2003. Dr. Holtzman is also involved in clinical and research activities at WUSM’s Alzheimer's Disease Research Center. Past honors include recipient of a Paul Beeson Physician Faculty Scholar Award in Aging Research, the 2003 Potamkin Prize from the American Academy of Neurology for research on Alzheimer's, election to the American Society for Clinical Investigation (2004), a MERIT award from the NIA (2004), and a 2006 recipient of the MetLife award on Alzheimer’s disease. In 2008, Dr. Holtzman was elected to the Institute of Medicine (IOM) of the National Academy of Sciences. He currently serves on the advisory council of the NINDS at the NIH.