Stefano Ricagno

Scientific Advisor at Dren Bio

Stefano Ricagno, PhD. is an Associate Professor of Biochemistry, PI of the Aggregation laboratory at the Department of Biosciences at the University of Milan (Italy) and senior PI and responsible for the laboratory of Structural Biology at the Institute for Molecular and Translational Cardiology at the IRCCS Policlinico San Donato, Milan (Italy).

After his master in Biological Sciences at the University of Pavia (Italy), he moved to Sweden where he accomplished his PhD in protein Crystallography at the Department of Medical Biochemistry and Biophysics, Karolinska Institute Stockholm. He worked as postdoctoral fellow at the “Architecture et Fonction des Macromolécules Biologiques” at the CNRS in Marseille, France. Then in 2006 Ricagno became senior postdoctoral fellow at the Department of Biomolecular Sciences and Biotechnology, University of Milan. In 2010 Ricagno obtained a position as Assistant Professor and then in 2015 he became associate professor at the Department of Biosciences at the University of Milan.

Ricagno’s scientific interest has been always focused on protein structures, structural enzymology and protein folding and misfolding. Since he moved to the University of Milan, he specifically focused on the structural bases of systemic amyloidoses. The study of the native fold of amyloidogenic proteins, the biophysical properties of aggregation propensity, amyloid aggregation and the structures of amyloid fibrils are to date the main topics of Ricagno’s research. AL amyloidosis, dialysis related amyloidosis, familial systemic amyloidosis due to D76N beta-2 microglobulin, amyotrophic lateral sclerosis are the main diseases Ricagno’s labs are focusing on.

He is member of the Editorial Board of Scientific Reports and Life (Basel) and acting as reviewers for many scientific journals such as Journal of American Chemical Society, Nature Communications, Science Advances.