Dr. Taha Merghoub is the Deputy Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine in New York. He is also the Margaret and Herman Sokol Professor of Oncology Research, Professor of Pharmacology, and Professor of Immunology Research in Medicine at Weill Cornell Medicine. Dr. Merghoub directs a translational tumor immunology laboratory and is currently investigating the means for developing immune-based therapies to treat cancer. In addition, some of his work aims to research the pathogenesis and treatment of melanoma and is directed in part at developing tools to study melanoma and immune responses in multiple cancers. His projects are heavily collaborative within the institution and across different disciplines with multiple entities. His projects can be divided into 4 categories: overcoming resistance to immune checkpoint blockade therapy by modulating the immune system, using the immune modulatory properties of modalities that target and kill tumor cells directly, defining biomarkers and genetic determinants of response to immune therapy, and developing a tissue repository for the immunotherapy and melanoma groups.