Purvesh Khatri

Dr. Khatri has more than 15 years of professional experience in the areas of bioinformatics, computational biology, and translational medicine. He is well known for work on the development of ontological and pathway analysis of high throughput molecular data, and for the integration and analysis of high throughput genomics and proteomics data. Dr. Khatri developed the first tool, Onto-Express, for analysis of microarray data using Gene Ontology. He expanded his work in ontological analysis to develop a suite of web-based open access tools, Onto-Tools. His recent work is focused on developing computational methods for integrated, multi-cohort analysis of publically available data to increase the sample size as well as better account for heterogeneity observed in real world patient population. Using these methods, he has identified highly specific and sensitive biomarkers for: (1) acute solid-organ transplant rejection, (2) cancers (pancreatic cancer, small cell and non-small cell lung cancer, mesothelioma), and (3) infectious diseases (sepsis, respiratory viral infections, tuberculosis).