Scientist I, In Vivo Pharmacology

Here at Kelonia Therapeutics, we aren’t just a preclinical company; we’re trailblazers in viral engineering, pushing the boundaries of in vivo lentiviral gene and cell therapy. We're not just a team; we're dreamers on a mission to bring the promise of cell and gene therapy to every patient in need.

At Kelonia, we've gathered a group of pioneers in cell and gene therapy to lead our journey, with extraordinary scientific founders at the helm, providing the cutting-edge technology that sets us apart. We're not just building a company; we're cultivating a culture—one that values both skill and care.

Are you ready to be a part of our remarkable journey? We are looking for someone exceptional to join our growing team as a Scientist I in the In Vivo Pharmacology group. This isn't just a job; it's an opportunity to contribute to groundbreaking therapies, to be part of a company's inception, and to make a transformative impact on patients' lives. If you're passionate about scaling a company from the ground up, making a real difference, and shaping the inclusive culture we're proud of, this opportunity is tailor-made for you. Join us and be a driving force in achieving excellence in viral engineering.

What You’ll Do:

• Lead in vivo murine model development and characterization for various programs.
• Design, plan, conduct, document, analyze and interpret preclinical in vivo studies in support of various programs.
• Work collaboratively to plan, execute, and analyze ex vivo characterization of multiple parameters such as bio-distribution and transduction efficiency.
• Prepare and present data and interpretations to cross-functional stakeholders.
• Help draft technical reports that document in vivo studies.
• Mentor and guide junior colleagues.

What You’ll Bring:

• Strong scientific expertise in Pharmacology or related discipline, PhD, and non-PhD candidates encouraged to apply (level based on experience)
• In-depth experience in animal handling and drug administration including i.v./i.p./s.c. dosing, in-study blood sampling, IVIS imaging, necropsy, tissue harvest and processing.
• Understands and implements study protocols in accordance with regulatory requirements for compliance with IACUC guidelines.
• Demonstrated initiative in experimental design, troubleshooting, and performing robust data analysis.
• Excellent organizational and documentation skills.
• Adaptable analytical person with a get-it-done attitude.
• Experience with humanized mouse models, engineered human T cells, and secondary ex vivo assays (eg. multicolor flow cytometry, PCR, MSD, IHC, ISH) is a plus.
• Ability to work collaboratively, meet deadlines, and prioritize and flexibly balance multiple workstreams.