Dr. Smagin is a Director of Pharmacology at Melior. He specializes in working with clients to custom-design experiments to evaluate therapeutic efficacy in models of anxiety, depression, sleep/wake (qEEG), and EEG-based seizure activity. He has a broad background and experience in functional neuroanatomy and neurochemistry as well as translational biomarkers for target-based pharmacology and safety assessments. Dr. Smagin is proficient in working with and managing external collaborators, contract research organizations and non-profit organizations.
Prior to joining Melior he worked at Lundbeck Research USA and AstraZeneca Pharmaceuticals (CNS/Psychiatry discovery) for >15 years where he designed and supervised neurochemical and pharmacological studies involving numerous disease areas, including evaluation of depression, anxiety, Parkinson’s (PD) and Alzheimer’s (AD) diseases and neurodegeneration.
Dr. Smagin received his medical training (MD) from Siberian Medical University (USSR) and a Ph.D. from Pavlov Institute of Experimental Medicine (St.Petersburg, Russia). He studied the neurochemistry and neuroendocrinology and neuroimmunology of stress-related disorders. As a postdoctoral fellow and later faculty member at LSU Medical Center in Shreveport, he studied neuroendocrinology of stress and its role in obesity, food intake and addiction. Dr. Smagin authored and co-authored over 40 peer-reviewed publications in various areas of neuropharmacology and neuropsychiatry including neurodegenerative diseases, AD, depression, anxiety and schizophrenia. Dr. Smagin has regulatory and compliance knowledge, including membership on the Institutional Animal Care and Use committee.
Current role
Head of Pharmacology & Toxicology at ProMIS Neurosciences
Senior Director, Head of Pharmacology at Step Pharma
Head of Pharmacology (Consultant) at Navitor Pharmaceuticals
Senior Director, Head Of Pharmacology & Disease Biology at Alltrna
Vice President & Head of Pharmacology at Galecto