Mitokinin
Katharina von Löhneysen, Ph.D has held various research positions since 2000. Katharina began their career as a Research Assistant at the University of Kassel, where they researched the involvement of fatty acid synthase in endocytosis in model organism Dictyostelium discoideum. Katharina also taught practical laboratory courses. From 2003 to 2013, they held three post-doctoral positions at The Scripps Research Institute. In these roles, they compared red cell proteome of hemolytic anemia patients with that of close relatives and controls, analyzed mass spectrometry data, processed blood samples and prepared resulting protein lysates for DIGE, investigated regulation and function of NAPDH oxidases, and studied intracellular transport of high-affinity IgE receptor in basophiles. From 2013 to 2017, they worked as a Scientist at TUNITAS THERAPEUTICS, INC., where they led the preclinical cell biology research component of their efforts to develop therapeutics for allergic asthma. Katharina was the scientific lead for IHC and FACS evaluation of samples from toxicology studies in non-human primates and a Phase I clinical trial, and helped design new molecular entities (NME) based on the results of their cell biology assays. Katharina is currently a Research Scientist at Mitokinin Inc, a position they have held since 2020.
Katharina von Löhneysen earned their Dr. rer nat (PhD) in Molecular Cell biology from the University of Kassel, Germany in 2003. Katharina had previously earned their Diploma in Biology (MS) in Genetics from the same university in 2000.
Mitokinin
Mitokinin is operates in the healthcare industry focusing on biotechnology business. Mitokinin has advanced small molecule therapeutics that specifically increase the activity of active-form PINK1. Importantly, Mitokinin’s compounds do not interfere with the endogenous regulation of PINK1. PINK1 is a master regulator of mitochondrial quality control. Mutations in PINK1 give rise to familial forms of Parkinson’s disease. Increased PINK1 activity rescues pathologies associated with neurodegenerative disease. Mitokinin has an accomplished team of neuroscientists, chemists, pharmacologists, and administrative professionals all focused on our mission: delivering disease-modifying therapies for neurodegenerative disease.