Nimbus Therapeutics
- Clinical Immunology Lead
Clinical Immunology Lead
Boston, United States
Job description
Nimbus has an outstanding opportunity for an exceptional Clinical Immunology Lead to join our team. This individual will serve as the medical immunology leader for our molecules in the immunology portfolio. In this capacity, the Clinical Immunology Lead will help define the scientific rationale and clinical tractability of our immunology pipeline molecules and define their development paths in multiple autoimmune and inflammatory diseases. Working closely with the discovery group and translational medicine team, this person will define the clinical development plans and medical strategy of our immunology assets. In addition, the Clinical Immunology lead will drive first in human studies and activities as well as proof of concept studies. This person may serve as the project leader for one of the immunology asset and will report to our Chief Medical Officer.
In This Role You Will:
- Provide strategic leadership, therapeutic expertise, and execution for Nimbus’ early Immunology portfolio
- Integrate scientific rationale, regulatory requirements, product development plan and commercials goals to build the Clinical Development Plan
- Develop approaches to demonstrate early activity and therapeutic promise through use of biomarker strategy in collaboration with Translational Medicine team & internal Immunology subject matter expertise
- Oversee the development of clinical activities across drug development studies within the immunology therapeutic area in collaboration with the clinical development teams
- Provide medical and scientific input into and/or lead key deliverables (INDs, CSRs, safety documents, publications, etc.)
- Identify and review new clinical and scientific research opportunities
- Contribute to the development of strategic initiatives, specific Business Development activities, and various organizational initiatives in Clinical Development
- Support leadership, including CMO, in building a cross-functional team in immunology and early development
- Be an active member of the development leadership team, the development operation team and governance teams
These Qualifications Will Help This Role Be Successful:
- MD, PhD, PharmD or equivalent degree preferably in Immunology or similar health discipline
- 8+ years’ experience in the biopharmaceutical industry or equivalent; substantial understanding of Immunology therapeutic area required
- Demonstrated track record executing on First-in-human/Phase 1 & Phase 2 trials
- Understanding of scientific methods and tools used in early clinical development including, biomarkers, translational modeling, and relevant clinical trial landscape
- Experience with site engagement, handling responses from health authorities, IRBs, ethic committees and investigator sites
- Strong experience and understanding running clinical studies with substantial collaboration with other clinical development functions including clinical operations, regulatory, data management, safety/PV and program leadership
- Broad understanding of biopharmaceutical drug development, including working knowledge of relevant ICH and GCP guidelines and regulations
- Excellent verbal and written communication and organizational skills required with demonstrated success in leading projects and interacting with cross functional teams
- Ability to navigate, problem-solve, execute, and lead in a dynamic, fast-paced and evolving environment leveraging an entrepreneurial mindset
- Strong experience working cross-functionally with internal and external collaborators
A Snapshot of Nimbus
Our Science
At Nimbus, we design breakthrough medicines. Utilizing our powerful structure-based drug discovery engine, we create potent and selective small molecule compounds targeting proteins that are known to be fundamental drivers of pathology in highly prevalent human diseases and which have proven difficult for other drug makers to tackle. With a decade-plus track record of success, we’ve built a world-class team in both computationally driven drug discovery and early clinical development while continuing to move the needle for patients.
Our Culture
Nimbus is a close-knit company (our employees are Nimbi, if you are curious!) that values a fast-paced, entrepreneurial, intellectual-stimulating, and collaborative environment. We live by our Core Values: Integrity, a Passion for Excellence, Teamwork, and Authentic Communication and strive to build a community where we bring out the best in each other professionally and personally.
Our Company
Founded in 2009, Nimbus is a private, growing biotechnology company headquartered in Boston, Massachusetts. Learn more about us by going to www.nimbustx.com
Join Nimbus. We are making a difference and you can too.
At Nimbus, we believe our diversity of backgrounds and experiences strengthens our community and our ability to design breakthrough medicines. We prioritize creating an inclusive, welcoming culture that promotes our core values and encourages every Nimbi to bring their whole selves to their work. Nimbus is proud to be an equal opportunity employer. We value and celebrate all our employees and recognize that our diversity and inclusion are keys to our success. Nimbus is committed to providing equal opportunity for all employees and applicants without regard to race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Nimbus does not accept unsolicited resumes from any source other than directly from candidates.
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