Charles O’Donnell

VP, Head of Computational Genomics & Data Sciences at Omega Therapeutics

Dr. Charles O’Donnell has over 15 years of data science and genomics experience, with an extensive background using data to solve scientific problems, specifically in genetic medicines. He has successfully led multi-disciplinary teams and has proven a broad range of technical and strategic expertise across data science, computational biology, machine learning, genomics and epigenomics, NGS, editing, gene therapy, proteomics, systems and network analysis, high performance computing, and data integration.

Prior to joining Omega, Charles was Head of the Computational Biology and Data Sciences function at Evelo Biosciences, and the first Head of Computational Biology and Data Sciences at Camp4 Therapeutics. Earlier in his career, he was the computational subject-matter expert in Biogen’s Epigenetics and Cell and Gene Therapy team and worked as a joint NRSA Postdoctoral Fellow in the Melton Lab of Harvard’s Stem Cell Institute and the Gifford Lab of MIT’s Computer Science and AI Laboratory.

Dr. O’Donnell received his Ph.D. in Electrical Engineering and Computer Science from MIT, working in the Berger and Devadas Labs at MIT’s Computer Science and AI Laboratory and the Lindquist Lab of the Whitehead Institute. He received his M.S. in Electrical Engineering and Computer Science from MIT and his B.S. in Computer Engineering from Columbia University.

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  • VP, Head of Computational Genomics & Data Sciences

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