Todd Margolis

Scientific Advisor at Rational Vaccines

Todd Margolis MD, PhD is the Albert and Edith Wolff Distinguished Professor and Chair of the John F. Hardesty MD Department of Ophthalmology and Visual Sciences at Washington University in St. Louis.

Dr. Margolis has a long-standing interest in regulation of infection with HSV. Prompted by his neuroscience background, his lab research has focused on how HSV and sensory neurons interact to regulate productive and latent viral infection.

In his clinical practice, Dr. Margolis cares for patients with complicated infectious and inflammatory eye disease. He is particularly well known for his clinical expertise in the areas of HSV and VZV eye disease. He is currently working as the protocol chair for an AIDS Malignancy Collaborative study (AMC -104), a feasibility study of OSSN surgical excision in HIV infected patients in 4 countries in west Africa.

During his career, Dr. Margolis has supervised 17 pre-doctoral students and 16 postdoctoral fellows in his lab, as well as over 100 clinical fellows (including 31 international fellows), many of whom conducted clinical research. Four of his fellowship trainees are currently chairs of departments of ophthalmology. He has over 160 peer reviewed publications in the scientific literature (H factor=46) and has received a number of awards, including the Jules Stein Vision Research Award, RPB Career Development Award, RPB Lew Wasserman Merit Award, RPB Senior Scientific Investigator Award, Faculty AOA Award and 2012 Heed Award. He has served on a number of NIH study sections, NEI council, as an executive editor of the American Journal of Ophthalmology, and as president of ARVO.


Timeline

  • Scientific Advisor

    Current role