Guido Kroemer

Scientific Advisor at Samsara Therapeutics

Guido Kroemer MD, PhD is Professor at the University of Paris Descartes and Inserm. Dr. Kroemer is a prominent researcher in the fields of autophagy and cancer biology. He is best known for the discovery that the permeabilization of mitochondrial membranes constitutes a decisive step in programmed cell death. Kroemer has explored the fine mechanisms of mitochondrial cell death control, the molecular pathways that explain the inhibition of cell death in cancer cells, upstream of or at the level of mitochondria, and the mechanisms that make cancer cell death immunogenic. In recent years, he has worked on the link between cellular stress and autophagy, as well as the stimulation of autophagy for improving health span and lifespan in model organisms. His work has had far reaching implications for the comprehension, detection and therapeutic manipulation of cellular demise. He has published some 1100 papers in leading journals, with an h-index of 217. He is one of the 10 most cited life scientists in the world. Dr. Kroemer was founding editor-in-chief of Cell Death & Disease and is a member of EMBO. His MD and PhD are from the University of Innsbruck, and has a second PhD from the Autonomous University of Madrid.

Timeline

  • Scientific Advisor

    Current role